I've had my MSI laptop for a couple months now. Here's my experience so far:
I'm moderately geeky, so I passed on a few laptop deals because I knew I wanted a Core 2 Duo processor. The 2.2 GHz processor in my A6000 handles common tasks very well, and it knocks out small video rendering tasks quickly.
I also held out for HDMI-out because I knew that I wanted the option of connecting to our TV. The integrated Nvidia graphics chip borrows memory from the 4 GB of RAM that came with the laptop, which is fine for HD video viewing. I play games on my Wii, so I don't need much more video power than that. Ubuntu presented me with an option to download updated drivers from Nvidia, making configuring two displays simple and painless. This driver also enables all the 3D bells and whistles available on GNOME desktop systems.
The 16-inch screen is bright, crisp, and glossy. I can see my reflection if I'm around direct sunlight, making it hard to see the screen. The 720p resolution is perfect for DVDs, Youtube videos, and home videos.
The keyboard is "full-size" with some caveats. The right-hand pinky finger keys feel kind of cramped, especially the Shift key. The designers clearly made some sacrifices to squeeze in a number pad to the right of the keyboard. The number pad is small, but it's better than no number pad. It's been especially helpful for entering scores into my district's new online gradebook.
As for ports, the A6000 has the standard selection: three USB, one VGA, 1 audio-out, 1 audio-in, and an SD card reader. When I first started shopping around, I looked hard at Dell Studio laptops, because I wanted to connect my DV camcorder via Firewire. Once I saw this laptop, I resolved to sell the DV digicam and make the switch to USB video file transfer. I haven't looked back. MSI added an ExpressCard slot as well, but I have no idea what to do with it.
I booted the default Windows 7 OS just long enough to burn recovery discs, and then I wiped the 320 GB hard drive and installed Ubuntu 9.10 64-bit. The essential features worked out of the box: wi-fi, trackpad, even the built-in webcam and microphone. The Ubuntu update manager found the rest of the important updates to make my computer run smoothly. One hardware drawback has been limited trackpad options. MSI uses Sentelic trackpad hardware, which is just starting to gain support in recent releases of the Linux kernel. In practice, this means I can't turn off tap-to-click, and I don't have scrolling functions on my trackpad. I have yet to patch my kernel and install the necessary modules and config files to get full control over my trackpad. I may simply wait until support is baked in to Ubuntu
Overall, I've been very happy with this MSI model. I have no regrets about bailing out on my old Apple PowerBook G4.